Pediatric sinonasal undifferentiated carcinoma: case report and literature review.

aggressive malignancy arising from the nasal cavity and paranasal sinuses. Sinonasal undifferentiated carcinoma was first reported in 1986 by Frierson et al, and since then less than 100 cases have been reported in the literature.1 One previous pediatric case has been described in a 12-year-old boy in India.2 Sinonasal undifferentiated carcinoma is histologically classified as part of a spectrum of neuroendocrine carcinomas originating from the Schneiderian epithelium or the nasal ectoderm in the paranasal sinuses.1 Here, we report only the second case of SNUC to arise in childhood involving a teenager with disease arising from the nasal cavity and extending through the paranasal air sinuses into the anterior cranial fossa and brain.